Patent Number: 7,612,239

Title: Method for asymmetric alkynylation of alpha-imino esters

Abstract: Method for the preparation of asymmetric alkynylated .alpha.-amino esters of the formula ##STR00001## wherein R.sub.1 and R.sub.2 are independently optionally substituted alkyl cycloalkyl, aryl or heteroaryl, and Y is hydrogen or a nitrogen protecting group.

Inventors: Chan; Albert S (Hung Hom, HK), Ji; Jian-Xin (Nashville, TN), Wu; Jing (Hangzhou Zhejiang, CN)

Assignee: The Hong Kong Polytechnic University

International Classification: C07C 209/60 (20060101)

Expiration Date: 1/03/02017