Patent Number: 7,708,984

Title: Methods of treatment with anitbodies to a chemokine expressed in inflamed adenoid

Abstract: The present invention provides nucleotide and amino acid sequences that identify and encode a novel expressed chemokine (ADEC) from inflamed adenoid tissue. The present invention also provides for antisense molecules to the nucleotide sequences which encode ADEC, expression vectors for the production of purified ADEC, antibodies capable of binding specifically to ADEC, hybridization probes or oligonucleotides for the detection of ADEC-encoding nucleotide sequences, genetically engineered host cells for the expression of ADEC, diagnostic tests for inflammation or disease based on ADEC-encoding nucleic acid molecules or antibodies capable of binding specifically to ADEC.

Inventors: Guegler; Karl J. (Menlo Park, CA), Hawkins; Phillip R. (Mountain View, CA), Wilde; Craig G. (Sunnyvale, CA), Seilhamer; Jeffrey J. (Los Altos Hills, CA)

Assignee: Incyte Corporation

International Classification: A61K 38/19 (20060101)

Expiration Date: 5/04/12018