Patent Number: 7,709,234

Title: .alpha.-1,3-fucosyltransferase

Abstract: The invention provides a novel species of .alpha.-1,3-fucosyltransferase expressed by a gene cloned from animal cells, a cDNA coding for the .alpha.-1,3-fucosyltransferase, a method of detecting, or inhibiting the production of, the .alpha.-1,3-fucosyltransferase which involves the use of the cDNA, a recombinant vector containing the DNA as an insert, a cell harboring the recombinant vector, and a method of producing same. The .alpha.-1,3-fucosyltransferase of the invention is useful in the production of carbohydrate chains having useful physiological activity, for example sialyl Lewis x, and modifications thereof.

Inventors: Sasaki; Katsutoshi (Tokyo, JP), Miura; Kazumi (Kanagawa, JP), Hanai; Nobuo (Kanagawa, JP), Nishi; Tatsunari (Tokyo, JP)

Assignee: Kyowa Hakko Kirin Co., Ltd.

International Classification: C12N 9/10 (20060101); C12N 15/54 (20060101); C12P 19/18 (20060101)

Expiration Date: 5/04/12018