Patent Number: 7,709,450

Title: Stimulation of vascularization with VEGF-B-186

Abstract: VEGF-B is shown to be needed for cardiac muscle revascularization after heart infarction, and methods of promoting or stimulating vascular development, e.g. angiogenesis and/or arteriogenesis, particularly in ischemic mammals, are disclosed.

Inventors: Eriksson; Ulf (Stockholm, SE), Li; Xuri (Stockholm, SE), Carmeliet; Peter (Zwijnaarde, BE), Collen; Desire (Zwijnaarde, BE)

Assignee: Ludwig Institute for Cancer Research

International Classification: A61K 31/70 (20060101)

Expiration Date: 5/04/12018