Patent Number: 7,709,476

Title: Isoquinolinone potassium channel inhibitors

Abstract: The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ##STR00001##

Inventors: Dinsmore; Christopher J. (Newton, MA), Bergman; Jeffrey M. (Sellersville, PA), McIntyre; Charles J. (Lansdale, PA), Claremon; David A. (Maple Glen, PA)

Assignee: Merck Sharp & Dohme Corp.

International Classification: C07D 217/16 (20060101); A61K 31/47 (20060101)

Expiration Date: 5/04/12018