Patent Number: 7,709,502

Title: Substituted 2-(2,6-dioxopiperidin-3-yl)-phthalimides and 1-oxoisoindolines

Abstract: Substituted 2-(2,6-dioxopiperidin-3-yl)phthalimides and 1-oxo-2-(2,6-dioxopiperidin-3-yl)isoindolines are disclosed. The compounds are useful, for example, in reducing the levels of TNF.alpha. in a mammal.

Inventors: Muller; George W. (Bridgewater, NJ), Stirling; David I. (Branchburg, NJ), Chen; Roger Shen-Chu (Edison, NJ)

Assignee: Celgene Corporation

International Classification: A61K 31/445 (20060101); C07D 401/04 (20060101)

Expiration Date: 5/04/12018