Patent Number: 7,709,539

Title: Therapeutic use of resveratrol for hyperglycemia

Abstract: Resveratrol, an antioxidant found in various fruits, vegetables, grapes, and red wines, has been shown to have free radical scavenging, anti-inflammatory and anti-thrombogenic activities in biological systems. Moreover, resveratrol has also been shown to be a good cancer preventive chemical and has been recommended as a food supplement for health benefits. Resveratrol can effectively lower the blood sugar in both type 1 (insulin-dependent diabetes mellitus, IDDM) and type 2 (insulin-independent diabetes mellitus, NIDDM) diabetic rats. Resveratrol could also delay the onset of the insulin-resistant phenotype in experimental rats with prolonged injection of insulin. Further, resveratrol simultaneously slows down the body weight increment compared with untreated insulin resistant animals.

Inventors: Chen; Jan-Kan (Tao-Yuan, TW), Hung; Li-Man (Tao-Yuan, TW)

Assignee: Chang Gung University

International Classification: A61K 31/05 (20060101); A61P 3/10 (20060101)

Expiration Date: 5/04/12018