Patent Number: 7,709,618

Title: BTL-II nucleic acids

Abstract: The invention provides isolated BTL-II proteins, nucleic acids, antibodies, antagonists, and agonists and methods of making and using the same. Diagnostic, screening, and therapeutic methods using the compositions of the invention are provided. For example, the compositions of the invention can be used for diagnosis and treatment of inflammatory bowel diseases and for enhancing a mucosal immune response to an antigen.

Inventors: Baum; Peter R (Seattle, WA), Escobar; Sabine S (Issaquah, WA), Viney; Joanne L (Seattle, WA)

Assignee: Immunex Corporation

International Classification: C07H 21/04 (20060101); C12N 5/10 (20060101); C12P 21/02 (20060101)

Expiration Date: 5/04/12018