Patent Number: 7,709,640

Title: Nitrogenous heterocyclic compounds and process for making nitrogenous heterocyclic compounds and intermediates thereof

Abstract: The present invention provides nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof and a process for making thereof. The compounds have inhibitory activity on the phosphorylation of kinases, which inhibits the activity of such kinases. The invention also provides intermediate compounds useful in the process, as well as final products produced by the process, and salts or prodrugs thereof. The invention further provides a method of inhibiting kinases and treating disease states in a mammal by inhibiting the phosphorylation of kinases comprising administering an effective amount of a compound according to the invention to a patient in need thereof.

Inventors: Kanter; James (South San Francisco, CA), Pandey; Anjali (Fremont, CA), Robinson; James (Sacramento, CA), Scarborough; Robert M. (Half Moon Bay, CA)

Assignee: Millennium Pharmaceuticals, Inc.

International Classification: C07D 295/182 (20060101)

Expiration Date: 5/04/12018