Patent Number: 7,709,684

Title: Process for preparing substituted biphenyls

Abstract: A process for preparing substituted biphenyls of the formula I ##STR00001## in which the substituents are defined as follows: X is fluorine or chlorine; R.sup.1 is nitro, amino or NHR.sup.3; R.sup.2 is cyano, nitro, halogen, C.sub.1-C.sub.6-alkyl, C.sub.1-C.sub.6-alkenyl, C.sub.1-C.sub.6-alkynyl, C.sub.1-C.sub.6-alkoxy, C.sub.1-C.sub.6-haloalkyl, C.sub.1-C.sub.6-alkylcarbonyl or phenyl; R.sup.3 is C.sub.1-C.sub.4-alkyl, C.sub.1-C.sub.4-alkenyl or C.sub.1-C.sub.4-alkynyl; n is 1, 2 or 3, where in case that n is 2 or 3, the R.sup.2 radicals may also be different, which comprises reacting the compound of the formula II ##STR00002## in which Hal is halogen and X and R.sup.1 are as defined above, in the presence of a base and of a palladium catalyst selected from the group of: a) palladium-triarylphosphine or -trialkylphosphine complex with palladium in the zero oxidation state, b) salt of palladium in the presence of triarylphospine or trialkylphosphine as a complex ligand or c) metallic palladium, optionally applied to support, in the presence of triarylphosphine or trialkylphosphine, in a solvent, with a diphenylborinic acid (III) ##STR00003## in which R.sup.2 and n are as defined above, where the triarylphosphines or trialkylphosphines used may be substituted.

Inventors: Smidt; Sebastian Peer (Mannheim, DE), Dietz; Jochen (Mannheim, DE), Keil; Michael (Freinsheim, DE), Grote; Thomas (Wachenheim, DE)

Assignee: BASF SE

International Classification: C07C 211/45 (20060101); C07C 205/06 (20060101); C07C 211/48 (20060101)

Expiration Date: 5/04/12018