Patent Number: 7,711,420

Title: Closed-loop control of cardioprotective pre-excitation pacing

Abstract: Cardioprotective pre-excitation pacing may be applied to stress or de-stress a particular myocardial region delivering of pacing pulses in a manner that causes a dyssynchronous contraction. Such dyssynchronous contractions are responsible for the desired cardioprotective effects of pre-excitation pacing but may also be hazardous. Described herein is a method and system that uses measures of ventricular dyssynchrony or a patient's physiological response to ventricular dyssynchrony to control the delivery of cardioprotective pre-excitation pacing in closed-loop fashion.

Inventors: Baynham; Tamara Colette (Piscataway, NJ), Ni; Quan (Shoreview, MN), Cazares; Shelley M. (Washington, DC), Stalsberg; Kevin J. (White Bear Lake, MN), Zhang; Yi (Blaine, MN)

Assignee: Cardiac Pacemakers, Inc.

International Classification: A61N 1/00 (20060101)

Expiration Date: 5/04/12018