Patent Number: 7,713,530

Title: HIV-1 subtype isolate regulatory/accessory genes, and modification and derivatives thereof

Abstract: The invention describes HIV-1 subtype isolate regulatory/accessory genes, and modifications and derivatives thereof. The genes which are described are the tat, nef and rev genes. Consensus amino acid sequences are also disclosed. The invention also relates to a vaccine including two or more of the nucleotide sequences, and nucleotide sequences from the pol and/or gag genes of HIV-1.

Inventors: Williamson; Carolyn (Cape Town, ZA), van Harmelen; Joanne Heidi (Cape Town, ZA), Gray; Clive Maurice (Johannesburg, ZA), Bourn; William (Cape Town, ZA), Karim; Salim Abdool (Durban, ZA)

Assignee: The South African Medical Research Council

International Classification: A61K 39/38 (20060101); A61K 39/12 (20060101); A61K 39/21 (20060101); C07K 14/00 (20060101)

Expiration Date: 5/11/12018