Patent Number: 7,714,170

Title: Use of compounds and compositions for the treatment of amyloid diseases

Abstract: Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, especially A.beta. amyloidosis, such as observed in Alzheimer's disease, use in the reduction of A.beta. peptide in vivo, use in modulating APP processing, and use in modulating the activity of APP secretase.

Inventors: Snow; Alan D. (Lynnwood, WA), Hu; Qubai (Kirkland, WA), Cam; Judy A. (Bellevue, WA)

Assignee: Proteotech, Inc.

International Classification: C07C 33/00 (20060101); A61K 31/00 (20060101); C07C 209/00 (20060101); C07C 211/00 (20060101); C07C 233/00 (20060101); C07C 239/00 (20060101); C07C 275/00 (20060101); C07C 49/00 (20060101)

Expiration Date: 5/11/12018