Patent Number: 7,785,565

Title: Metal chelators and methods of their use

Abstract: Metal chelators of Formula I and Formula II are disclosed: ##STR00001## or a pharmaceutically acceptable salt thereof. Also disclosed are metal chelator-targeting moiety complexes, metal chelator-targeting moiety-metal conjugates, kits, and methods of their preparation and use in diagnosis and/or treatment of diseases and conditions, including, inter alia, cancer and thrombosis.

Inventors: Brechbiel; Martin Wade (Annandale, VA), Clifford; Thomas (Rockville, MD)

Assignee: The United States of America as represented by the Secretary, Department of Health and Human Services

International Classification: A61K 51/00 (20060101); A61M 36/14 (20060101)

Expiration Date: 8/31/12018