Patent Number: 7,785,567

Title: Growth hormone-releasing peptides in the treatment or prevention of atherosclerosis and hypercholesterolemia

Abstract: According to the invention there is provided a method of treatment or prophylaxis of atherosclerosis, hypercholesterolemia or a cardiovascular disease associated with atherosclerosis, which method comprises administration of one or more Growth Hormone Releasing Peptides (GHRPs) to a patient in need of such treatment or prophylaxis. There are also provided methods of reducing blood plasma cholesterol levels, as well as methods of modulating the expression of the scavenger receptor CD36 and genes involved in cellular cholesterol efflux.

Inventors: Ong; Huy (Ville Mont-Royal, CA), Marleau; Sylvie (Rosemere, CA), Tremblay; Andre (Laval-des-Rapides, CA)

Assignee: Valorisation-Recherche, Societe en Commandite

International Classification: A61K 49/00 (20060101); A61K 38/00 (20060101); C07K 4/00 (20060101)

Expiration Date: 8/31/12018