Patent Number: 7,785,830

Title: Expression vectors, transformed host cells and fermentation process for the production of recombinant polypeptides

Abstract: The present invention relates to an expression vector, comprising a polynucleotide encoding a fusion protein comprising the signal sequence of the gac gene of Pseudomonas diminuta and a polypeptide of interest, a prokaryotic host cell transformed with such an expression vector and a process for production of a polypeptide of interest using said host cell and said expression vector.

Inventors: Windisch; Jorg (Kramsach, AT), Schoergendorfer; Kurt (Langkampfen, AT), Palma; Norbert (Breitenbach a. Inn, AT), Knauseder; Franz (Kirchbichl, AT), Boehling; Hans (Kufstein, AT)

Assignee: Sandoz AG

International Classification: C12N 1/19 (20060101); C12N 15/11 (20060101); C12P 21/06 (20060101)

Expiration Date: 8/31/12018