Patent Number: 7,785,852

Title: Cleavage of nucleic acids

Abstract: The present invention relates to means for cleaving a nucleic acid cleavage structure in a site-specific manner. Enzymes, including 5' nucleases and 3' exonucleases, are used to detect and identify nucleic acids derived from microorganisms. Methods are provided which allow for the detection and identification of bacterial and viral pathogens in a sample.

Inventors: Dahlberg; James E. (Madison, WI), Brow; Mary Ann D. (Madison, WI), Lyamichev; Victor I. (Madison, WI)

Assignee: Third Wave Technologies, Inc.

International Classification: C12N 9/12 (20060101); C12N 9/22 (20060101); C07H 21/04 (20060101)

Expiration Date: 8/31/12018