Patent Number: 7,785,861

Title: Hyperphotosynthetic organisms

Abstract: The present disclosure identifies pathways and mechanisms to confer improved industrial fitness on engineered organisms. It also discloses engineered organisms having improved industrial fitness. Synthetic biologic engineering modules are disclosed that provide for light capture, carbon dioxide fixation, NADH production, NADPH production, thermotolerance, pH tolerance, flue gas tolerance, salt tolerance, nutrient independence and near infrared absorbance. The disclosed engineered organisms can include one or more of these modules. Also provided are methods of using the engineered organism to produce carbon-based products of interest, biomass or pharmaceutical agents.

Inventors: Devroe; Eric James (Malden, MA), Kosuri; Sriram (Cambridge, MA), Berry; David Arthur (Brookline, MA), Afeyan; Noubar Boghos (Lexington, MA), Skraly; Frank Anthony (Watertown, MA), Robertson; Dan Eric (Belmont, MA), Green; Brian (Watertown, MA), Ridley; Christian Perry (Acton, MA)

Assignee: Joule Unlimited, Inc.

International Classification: C12N 15/31 (20060101); C12N 15/52 (20060101); C12N 15/82 (20060101)

Expiration Date: 8/31/12018