Patent Number: 7,785,898

Title: Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood

Abstract: The present invention provides methods for identifying and/or enriching fetal cells from maternal blood, using as fetal cell markers the antibodies that the mother produces against paternally inherited fetal antigens. The fetal cell-maternal antibody complexes are identified and isolated using labelled agents that bind to the maternal antibodies. The present invention also provides fetal cells, isolated by use of said maternal antibodies, as a source of fetal DNA for prenatal genetic diagnosis of the fetus.

Inventors: Bohmer; Ralph M. (West St Kilda, AU)

Assignee: Genetic Technologies Limited

International Classification: G01N 33/564 (20060101); G01N 33/53 (20060101)

Expiration Date: 8/31/12018