Patent Number: 7,786,096

Title: Inhibition of antigen presentation with poorly catabolized polymers

Abstract: Methods to prevent the rejection of immunogenic tissues in an animal by administering a non-immunogenic, poorly catabolized molecule in an amount sufficient to inhibit an immune response are described herein. Also described are compositions that are useful for inhibiting immune responses in animals that are recipients of cellular transplants. For example, these methods and compositions can be used to prevent the rejection of xenografted and allografted tissues in an animal.

Inventors: Frost; Greogry I. (Solana Beach, CA), Borgstrom; Per (La Jolla, CA)

Assignee: Halozyme, Inc.

International Classification: A61K 31/721 (20060101); A61K 38/00 (20060101)

Expiration Date: 8/31/12018