Patent Number: 7,786,278

Title: Modified CEA nucleic acid and expression vectors

Abstract: The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and/or treating cancer. The invention relates to improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer. One such foreign DNA sequence is modified CEA nucleic acid.

Inventors: Parrington; Mark (Bradford, CA), Zhang; Linong (Concord, CA), Rovinski; Benjamin (Thornhill, CA), Gritz; Linda R. (Somerville, MA), Greenhalgh; Patricia (Bedford, MA)

Assignee: Sanofi Pasteur Limited

International Classification: C07H 21/02 (20060101)

Expiration Date: 8/31/12018