Patent Number: 7,820,664

Title: Inhibitors of MEK

Abstract: This invention concerns to N-(2-aylamino)aryl sulfonamides, which are inhibitors of MEK, methods of using such compounds in the treatment of hyperproliferative diseases, and to pharmaceutical compositions containing such compounds.

Inventors: Vernier; Jean-Michel (Laguna Niguel, CA), Maderna; Andreas (Stony Point, NY), Koh; Yung-hyo (Irvine, CA), Hong; Zhi (Chapel Hill, NC)

Assignee: Bayer Schering Pharma AG

International Classification: A61K 31/5025 (20060101); A61K 31/4355 (20060101); A61K 31/47 (20060101); A61K 31/423 (20060101); A61K 31/4184 (20060101); A61K 31/416 (20060101); C07D 237/26 (20060101); C07D 487/04 (20060101); C07D 239/74 (20060101); C07D 498/04 (20060101); C07D 471/04 (20060101); C07D 215/38 (20060101); C07D 261/20 (20060101); C07D 235/08 (20060101); C07D 231/56 (20060101); A61K 31/519 (20060101); A61K 31/517 (20060101); A61K 31/437 (20060101)

Expiration Date: 2018-10-26 0:00:00