Patent Number: 7,820,835

Title: Method for producing flavan derivatives

Abstract: The present invention provides a method for producing flavan derivatives having various substituent groups with controlling the stereochemistry. The method of the present invention includes the steps of: hydratively condensing a phenol compound expressed by formula (I) and an alcohol compound expressed by formula (II) to from an epoxide compound of formula (III); opening the epoxy ring of the epoxide compound of formula (III) to form an iodine-containing compound of formula (IV); and cyclizing the iodine-containing compound to form the flavan derivative of formula (V). ##STR00001##

Inventors: Suzuki; Keisuke (Tokyo, JP), Ohmori; Ken (Tokyo, JP), Higuchi; Takashi (Tokyo, JP)

Assignee: Tokyo Institute of Technology

International Classification: C07D 311/62 (20060101)

Expiration Date: 2018-10-26 0:00:00