Patent Number: 7,825,097

Title: Nucleotide vector vaccine for immunization against hepatitis

Abstract: Nucleotide vector comprising at least one gene or one complementary DNA coding for at least a portion of a virus, and a promoter providing for the expression of such gene in muscle cells. The gene may be the S gene of the hepatitis B virus. A vaccine preparation containing said bare DNA is injected into the host previously treated with a substance capable of inducing a coagulating necrosis of the muscle fibres.

Inventors: Davis; Heather Lynn (Dunrobin, CA), Whalen; Robert Gerald (Foster City, CA), Michel; Marie-Louise (Paris, FR)

Assignee: Institut Pasteur

International Classification: A01N 43/04 (20060101); A61K 31/70 (20060101); C12N 15/00 (20060101)

Expiration Date: 2019-11-02 0:00:00