Patent Number: 7,825,117

Title: Methods of modulating intestine epithelial functions

Abstract: The present invention relates to prokineticin 1 receptor antagonists and methods of using the same to modulate intestine epithelial functions and to treat inflammation in the intestine in a mammal.

Inventors: Mabus; John R. (East Greenville, PA), Palmer; Jeffrey M. (Chalfont, PA), Prouty; Stephen M. (Doylestown, PA), Hornby; Pamela J. (Penllyn, PA), Wade; Paul R. (Philadelphia, PA)


International Classification: A61K 31/53 (20060101); A61K 31/50 (20060101); A61K 31/513 (20060101)

Expiration Date: 2019-11-02 0:00:00