Patent Number: 7,825,162

Title: Abietane diterpenoid compound, and composition comprising extract of torreya nucifera, or abietane diterpenoid compounds or terpenoid compounds isolated from them for prevention and treatment of cardiovascular disease

Abstract: A method for treating cardiovascular disease, including hyperlipidemia and atherosclerosis, using abietane diterpenoid compound or terpenoid compound isolated from Torreya nucifera as an effective ingredient. The abietane diterpenoid compound or terpenoid compound isolated from Torreya nucifera not only excellently inhibits oxidation of low-density lipoprotein (LDL), but also effectively inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity.

Inventors: Jeong; Tae-Sook (Taejeon-si, KR), Lee; Woo-Song (Taejeon-si, KR), Kim; Hyoung-Chin (Taejeon-si, KR), Choi; Yang-Kyu (Taejeon-si, KR), Kim; Ju-Ryoung (Taejeon-si, KR), An; So-Jin (Taejeon-si, KR), Im; Kyoung-Ran (Taejeon-si, KR), Jang; Ki-Chang (Jeju Province, KR), Moon; Og-Sung (Taejeon-si, KR), Son; Jun-Seock (Taejeon-si, KR)

Assignee: Korea Research Institute of Bioscience and Biotechnology

International Classification: A61K 31/17 (20060101)

Expiration Date: 2019-11-02 0:00:00