Patent Number: 7,825,251

Title: Process for producing carbostyril derivatives

Abstract: The present invention provides a process for producing carbostyril derivatives (I) which are known to be useful as medical drug such as antithrombotic agent, cerebral circulation improver, anti-inflammatory agent, antiulcer agent, etc. in a high yield and a high purity. The carbostyril derivatives (I) can be produced by reacting a carbostyril derivative (II) with a tetrazole derivative (III) in the presence of a phase transfer catalyst. ##STR00001##

Inventors: Aki; Shinji (Itano-gun, JP), Kurimura; Muneaki (Rockville, MD), Nishi; Takao (Itano-gun, JP), Minamikawa; Junichi (Naruto, JP), Tominaga; Michiaki (Itano-gun, JP), Fukuyama; Norihiro (Tokushima, JP), Yamamoto; Akihiro (Tokushima, JP)

Assignee: Otsuka Pharmaceutical Co., Ltd.

International Classification: C07D 215/16 (20060101)

Expiration Date: 2019-11-02 0:00:00