Patent Number: 7,826,974

Title: Preliophic moleculator using electric fields and gradients for manipulating molecules

Abstract: Apparatus and methods of using the apparatus for inducing movement and interaction of molecules in an electric field of an electrophoretic device that is circular in configuration to mimic a living cell. The circular electrophoretic device supports an isoelectric focusing medium, such as a gel on a gel plate with one charged circular pole at the center and an oppositely charged concentric pole at the perimeter of the plate whereupon molecular substances having electronegative or electropositive charges placed in the gel will tend to migrate toward the oppositely charged pole to their isoelectric points, allowing researchers to devise experiments with multiple substances to track pathways of interaction during osmotic diffusion and polar directed migration through the medium that parallel pathways in a biological cell, the device having a thermal control for regulating the temperature of the analytical experiments using the device.

Inventors: Smith; Roulette W. (Stanford, CA), Shadel; Robert R. (San Francisco, CA)


International Classification: G01N 33/48 (20060101); C12M 1/00 (20060101); G01N 31/00 (20060101); G06G 7/48 (20060101)

Expiration Date: 2019-11-02 0:00:00