Patent Number: 7,951,531

Title: Flavivirus NS5A proteins for the treatment of HIV

Abstract: GB virus C (GBV-C or hepatitis G virus) is a flavivirus that frequently leads to chronic viremia in humans. The invention provides compositions and methods involving a-GBV-C NS5A peptide or polypeptide for inhibiting and treating HIV infections.

Inventors: Stapleton; Jack T. (Iowa City, IA), Xiang; Jinhua (Iowa City, IA), Chang; Qing (Iowa City, IA), McLinden; James (Coralville, IA)

Assignee: University of Iowa Research Foundation

International Classification: C12Q 1/70 (20060101); A61K 39/21 (20060101); A61K 39/29 (20060101)

Expiration Date: 2019-05-31 0:00:00