Patent Number: 7,968,694

Title: Tuberculosis antigen detection assays and vaccines

Abstract: The present invention relates to isolated Tuberculosis (TB) antigens that are useful in therapeutic and vaccine compositions for stimulating a TB specific immunological response. The identified antigens are also useful in diagnostic assays to determine the presence of active TB in an individual. Accordingly, the present invention includes polypeptide molecules, nucleic acid molecules, vaccine compositions, diagnostic assays, and methods of diagnosis and monitoring treatment related to these TB antigens.

Inventors: Campos-Neto; Antonio (Westborough, MA), Kashino; Suely S. (Boston, MA)

Assignee: Forsyth Dental Infirmary for Children

International Classification: C07H 21/04 (20060101); C07H 21/02 (20060101); A61K 39/04 (20060101)

Expiration Date: 2019-06-28 0:00:00