Patent Number: 8,067,219

Title: Polynucleotide encoding an ATP binding cassette transporter 1 (ABC1) polypeptide

Abstract: The invention features ABC1 nucleic acids and polypeptides for the diagnosis and treatment of abnormal cholesterol regulation. The invention also features methods for identifying compounds for modulating cholesterol levels in an animal (e.g., a human).

Inventors: Hayden; Michael R. (Vancouver, CA), Brooks-Wilson; Angela R. (Richmond, CA), Pimstone; Simon N. (Vancouver, CA)

Assignee: Xenon Pharmaceuticals Inc.

International Classification: C12N 9/16 (20060101); C12N 1/20 (20060101); C12N 1/00 (20060101); C07H 21/04 (20060101); C12N 15/00 (20060101); C12N 5/02 (20060101)

Expiration Date: 2020-11-29 0:00:00