Patent Number: 8,218,840

Title: Method and device for selectively targeting cells within a three-dimensional specimen

Abstract: The invention provides an apparatus for electromagnetically affecting a particle of interest in a specimen. The apparatus includes (a) a stage capable of supporting the specimen; (b) a detector including at least one camera, wherein the detector is capable of resolving a particle of interest within the specimen; (c) a means for locating the particle of interest in three dimensions; (d) a means for focusing electromagnetic radiation to a focal volume within the specimen; and (e) a means for adjusting the relative positions of the stage and electromagnetic radiation focusing means, thereby positioning the particle of interest within the focal volume.

Inventors: Eisfeld; Timothy M (San Diego, CA), Koller; Manfred R (San Diego, CA), Palsson; Bernhard O (San Diego, CA)

Assignee: Intrexon Corporation

International Classification: G06K 9/00 (20060101)

Expiration Date: 2020-07-10 0:00:00