Patent Number: 8,299,020

Title: Antimicrobial peptides and methods of their use

Abstract: The present invention relates to a novel Paenibacillus polymyxa strain, OSY-DF, and its bioactive mutants. Also provided is a method for using a novel antimicrobial peptide, paenibacillin, isolated from the bacterial strain OSY-DF, and its bioactive variants or fragments. The invention also relates to antimicrobial compositions containing same and methods of their use.

Inventors: Yousef; Ahmed El-Meleigy (Columbus, OH), He; Zengguo (Columbus, OH), Yuan; Chunhua (Columbus, OH), Zhang; Liwen (Delaware, OH), Kisla; Duygu (Izmir, TR)

Assignee: The Ohio State University Research Foundation

International Classification: A01N 37/18 (20060101); A61P 31/04 (20060101); A61K 38/00 (20060101); C07K 5/00 (20060101); C07K 7/00 (20060101); C07K 16/00 (20060101); C07K 17/00 (20060101)

Expiration Date: 2020-10-30 0:00:00