Patent Number: 8,491,897

Title: Treatment of neuropathic pain using anti-thrombospondin antibodies

Abstract: The present invention describes methods and compositions for modulating synaptogenesis and axon and/or dendritic growth. The methods include the use of agents that modulate a thrombospondin and/or an .alpha.2.delta. subunit of a calcium channel.

Inventors: Eroglu; Cagla (Durham, NC), Barres; Ben A. (Palo Alto, CA)

Assignee: The Board of Trustees of the Leland Stanford Junior University

International Classification: A61K 39/395 (20060101)

Expiration Date: 2021-07-23 0:00:00