Patent Number: 8,496,945

Title: Nanoparticle delivery systems for membrane-integrating peptides

Abstract: Compositions which comprise emulsions of nanoparticles for delivery of membrane-integrating peptides are described. The nanoparticles comprise a liquid hydrophobic core coated with a lipid/surfactant layer which contains the membrane-integrating peptides. Methods to use such compositions are also described.

Inventors: Schlesinger; Paul (University City, MO), Soman; Neelesh (St. Louis, MO), Lanza; Gregory (St. Louis, MO), Wickline; Samuel A. (St. Louis, MO)

Assignee: Washington University

International Classification: A61K 9/00 (20060101); A61K 38/00 (20060101)

Expiration Date: 2021-07-30 0:00:00