Patent Number: 8,497,286

Title: Organic compounds

Abstract: The present invention relates to a compound of the formula I ##STR00001## wherein R1, R2, R3, R4 and R5 are as defined in the specification, for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations a compound of that class; a method of treatment comprising administering a compound of that class and a method for its manufacture.

Inventors: Yokokawa; Fumiaki (Tsukuba, JP), Ehara; Takeru (Tsukuba, JP), Kawakami; Shimpei (Tsukuba, JP), Irie; Osamu (Tsukuba, JP), Suzuki; Masaki (Tsukuba, JP), Hitomi; Yuko (Tsukuba, JP), Toyao; Atsushi (Tsukuba, JP)

Assignee: Novartis AG

International Classification: A61K 31/444 (20060101); C07D 211/32 (20060101)

Expiration Date: 2021-07-30 0:00:00