Patent Number: 8,501,240

Title: Compositions comprising an active agent

Abstract: The present invention provides a highly dispersible formulation comprising an active agent and a dipeptide or tripeptide comprising at least two leucyl residues. The composition of the invention possesses superior aerosol properties and is thus preferred for aerosolized administration to the lung. Also provided are a method for (i) increasing the dispersibility of an active-agent containing formulation for administration to the lung, and (ii) delivery of the composition to the lungs of a subject.

Inventors: Kuo; Mei-chang (Palo Alto, CA), Lechuga-Ballesteros; David (San Jose, CA)

Assignee: Novartis AG

International Classification: A61K 9/14 (20060101); A61K 38/05 (20060101); A61K 38/06 (20060101)

Expiration Date: 2021-08-06 0:00:00