Patent Number: 8,507,698

Title: Artemisinin derivatives for the treatment of melanoma

Abstract: The invention relates to Artemisinin derivatives of general formula (I) ##STR00001## wherein A and B are as defined in the specification. Compounds (I) have proved able to inhibit cell proliferation, in particular of uveal melanoma cells, and can therefore be used, either alone or in association with other antitumoral drugs, for the preparation of medicaments intended for the treatment of malignant melanoma.

Inventors: Villanova; Luigi (Zollino, IT), Villanova; Azzurra (Zollino, IT), Villanova; Luciano (Zollino, IT)

Assignee: Lachifarma S.R.L. Laboratorio Chimico Farmaceutico Salentino

International Classification: C07D 309/00 (20060101); A61K 31/335 (20060101)

Expiration Date: 2021-08-13 0:00:00