Patent Number: 8,512,744

Title: Sustained release micropellets and process for producing the same

Abstract: Sustained release micropellets showing a stable controlled-release of a drug without being affected by the changes in pH value etc., characterized by being produced by coating core particles with a layer containing a water-soluble drug and further forming a film layer containing a water-insoluble polymer compound and a plasticizer on the thus obtained particles, locating a water-soluble filler layer between the water soluble drug-containing layer and the film layer, and having an average particle size of 300 .mu.m or less; medicinal compositions containing these micropellets; and a process for producing the same.

Inventors: Yoneda; Fumio (Matsubara, JP), Hamano; Fumiya (Matsubara, JP), Kitano; Eisaku (Matsubara, JP), Hosono; Tetsuya (Matsubara, JP)

Assignee: Fujimoto Co., Ltd.

International Classification: A61K 9/26 (20060101); A61K 9/22 (20060101); A61K 9/20 (20060101)

Expiration Date: 2021-08-20 0:00:00