Patent Number: 8,574,837

Title: System for screening agonists/antagonists of cellular signaling pathways

Abstract: The present invention identifies a method for investigating the response of a cell membrane-associated protein in a living cell to a drug by labeling the protein with a visual marker, and also selectively labeling the membrane portion of the protein with another visual marker, such that upon exposure of the cell to a stimulus, the translocation of the cell membrane-associated protein may be observed directly.

Inventors: Wang; Yu (Madison, WI), McMahon; Andrew P. (Lexington, MA)

Assignee: President and Fellows of Harvard College

International Classification: C12Q 1/68 (20060101)

Expiration Date: 1/05/12017