Patent Number: 8,575,134

Title: Aminocarboxylic acid derivative and medicinal use thereof

Abstract: The present invention relates to a compound represented by the formula (I), a salt thereof, an N-oxide form thereof, a solvate thereof, or a prodrug thereof, and a medicament containing the same. The compound represented by the formula (I) has an ability to bind to an S1P receptor (particularly, EDG-1, EDG-6, and/or EDG-8) and is useful for preventing and/or treating for rejection to transplantation, graft-versus-host disease, autoimmune diseases, allergic diseases, neurodegenerating diseases, and the like. ##STR00001## wherein all symbols are described in the specification.

Inventors: Habashita; Hiromu (Osaka, JP), Kurata; Haruto (Osaka, JP), Nakade; Shinji (Tsukuba, JP)

Assignee: Ono Pharmaceutical Co., Ltd.

International Classification: A01N 55/08 (20060101); C07D 205/00 (20060101)

Expiration Date: 1/05/12017