Patent Number: 8,575,143

Title: 3-aryl-substituted quinazolones, and uses thereof

Abstract: Compounds represented by Structural Formula (I): ##STR00001## are useful, for example, in the effective killing or reducing the rate of proliferation of cancer cells, such as in patients suffering from cancer. In addition to the compounds themselves, the invention provides pharmaceutical compositions of the compounds and method of treatment using the compounds.

Inventors: Qi; Longwu (West Lafayette, IN), Venkat; Raj Gopal (Salt Lake City, UT), Pierce; Michael (Salt Lake City, UT), Robbins; Paul B. (Park City, UT), Sahasrabudhe; Sudhir R. (Sandy, UT), Selliah; Robert (Midvale, UT)

Assignee: Prolexys Pharmaceuticals, Inc.

International Classification: A01N 55/02 (20060101); C07D 239/70 (20060101); C07D 223/00 (20060101)

Expiration Date: 1/05/12017