Patent Number: 8,580,751

Title: Esterified .alpha.-galactosylceramide

Abstract: The invention provides esterified .alpha.-galactosylceramides effective for cancer treatment and the like, and a medicament containing same. In particular, the invention relates to a compound represented by the formula (I): ##STR00001## wherein R.sup.1 is a hydrocarbon group having a carbon number of 1 to 30, R.sup.2 is a hydrocarbon group having a carbon number of 1 to 20, R.sup.3 is a hydrogen atom or hydrocarbon group having a carbon number of 1 to 5, R.sup.4 and R.sup.5 are the same or different and each is a hydrogen atom or a hydrocarbon group having a carbon number of 1 to 5, or R.sup.4 and R.sup.5 in combination form a divalent hydrocarbon group having a carbon number of 1 to 5, and optionally form a ring structure together with the adjacent ethylenedioxy, or a salt thereof.

Inventors: Shiozaki; Masao (Kanagawa, JP), Tashiro; Takuya (Kanagawa, JP), Mori; Kenji (Kanagawa, JP), Nakagawa; Ryusuke (Kanagawa, JP), Watarai; Hiroshi (Kanagawa, JP), Taniguchi; Masaru (Kanagawa, JP)

Assignee: Riken

International Classification: C07H 15/06 (20060101); A61K 31/70 (20060101)

Expiration Date: 2022-11-12 0:00:00