Patent Number: 8,586,007

Title: Co-polymer stabilizers for hydrofluoroalkane dispersions

Abstract: The use of biodegradable and biocompatible lactide-based nonionic amphiphiles to stabilize a model drug (salbutamol base) dispersion in hydrofluoroalkane (HFA) propellant is disclosed. The results have industrial applicability to the development of HFA-based dispersion pressurized metered-dose inhaler formulations.

Inventors: Da Rocha; Sandro R. P. (Troy, MI), Wu; Libo (Detroit, MI)

Assignee: Wayne State University

International Classification: A61K 9/12 (20060101); A61K 47/30 (20060101); A61K 47/32 (20060101)

Expiration Date: 1/19/12018