Patent Number: 8,715,213

Title: Bone metabolism improving agent

Abstract: The present invention has as an object to provide a bone metabolism improving agent that improves bone metabolism in a chronic renal failure patient receiving blood purification therapy such as hemodialysis, hemofiltration and hemodiafiltration. An acetic acid- and/or acetate salt-free bone metabolism improving agent that contains citric acid and/or a citrate salt as electrolytes and further contains another/other electrolyte/electrolytes and glucose solely or in combination is provided. A bone metabolism improving agent formulated into a dialysate or a substitution fluid having effects of improving bone metabolism including bone metabolism improvement in adynamic bone disease and especially in bone agenesis is also provided.

Inventors: Yamazaki; Hidehiro (Tokyo, JP), Ohki; Toshihiro (Tokyo, JP), Inaba; Tomio (Tokyo, JP), Sakaguchi; Naomi (Tokyo, JP)

Assignee: Ajinomoto Co., Inc.

International Classification: A61M 37/00 (20060101); C02F 1/44 (20060101)

Expiration Date: 5/06/12018