Patent Number: 8,715,658

Title: Methods for treating conditions mediated by the inflammatory cytokine cascade using GAPDH inhibitors

Abstract: The present invention is directed to a method of treating a subject at risk for or having a condition mediated by an inflammatory cytokine cascade comprising administering to the subject an amount of a GAPDH inhibitor effective to treat the subject at risk for or having a condition mediated by an inflammatory cytokine cascade.

Inventors: Tracey; Kevin (Old Greenwich, CT), Parrish; William (Hudson, MA)

Assignee: The Feinstein Institute for Medical Research

International Classification: A61K 39/395 (20060101); A61K 38/02 (20060101); C07K 16/40 (20060101)

Expiration Date: 5/06/12018