Patent Number: 8,715,673

Title: Staphylococcus aureus specific antibodies and uses thereof

Abstract: The present invention provides antagonizing antibodies that bind to S. aureus alpha-toxin. The invention further provides a method of obtaining such antibodies and antibody encoding nucleic acids. The invention further relates to therapeutic methods for use of these antibodies for the treatment and/or prevention of staphylococcal disease, including, for example, pneumonia, bacteremia, sepsis, eye infection, and abscess.

Inventors: Foletti; Davide Luciano (Menlo Park, CA), Chaparro Riggers; Javier Fernando (San Mateo, CA), Glanville; Jacob Eli Gunn (San Francisco, CA), Shaughnessy; Lee Mary Beth (Madison, WI), Shelton; David Louis (Oakland, CA), Strop; Pavel (San Mateo, CA), Zhai; Wenwu (Redwood City, CA)

Assignee: Rinat Neuroscience Corp.

International Classification: A61K 39/40 (20060101)

Expiration Date: 5/06/12018