Patent Number: 8,716,324

Title: Tricyclic indeno-pyrrole derivatives as serotonin receptor modulators

Abstract: The present invention generally relates to a series of compounds, to pharmaceutical compositions containing the compounds, and to use of the compounds and compositions as therapeutic agents. More specifically, compounds of the present invention are tricyclic indeno-pyrrole compounds. These compounds are serotonin receptor (5-HT) ligands and are useful for treating diseases, disorders, and conditions wherein modulation of the activity of serotonin receptors (5-HT) is desired (e.g. anxiety, depression and obesity).

Inventors: Bennani; Youssef L. (Boston, MA), Huck; Bayard (Sudbury, MA), Robarge; Michael J. (Burton, OH)

Assignee: Athersys, Inc.

International Classification: A61K 31/403 (20060101); C07D 209/70 (20060101)

Expiration Date: 5/06/12018