Patent Number: 8,721,618

Title: Device for actively removing a target cell from blood or lymph of a vertebrate subject

Abstract: Devices, systems, and methods are described herein for controlling the level of one or more target cell types in the blood fluid and/or lymph fluid of a vertebrate subject. Devices, systems, and methods are provided that include a body defining at least one lumen configured for fluid flow; at least one controllable flow barrier to the at least one lumen; one or more sensor configured to detect one or more target cell types in blood fluid or lymph fluid of a vertebrate subject; at least one treatment region disposed within the at least one lumen; at least one reactive component disposed in the at least one treatment region; and at least one controller in communication with the one or more sensor and in communication with the at least one controllable flow barrier to the at least one lumen.

Inventors: Hyde; Roderick A. (Redmond, WA), Ishikawa; Muriel Y. (Livermore, CA), Jung; Edward K. Y. (Bellevue, WA), Langer; Robert (Newton, MA), Leuthardt; Eric C. (St. Louis, MO), Myhrvold; Nathan P. (Bellevue, WA), Sweeney; Elizabeth A. (Seattle, VT), Wood, Jr.; Lowell L. (Bellevue, WA)

Assignee: The Invention Science Fund I, LLC

International Classification: A61M 31/00 (20060101)

Expiration Date: 5/13/12018