Patent Number: 8,722,051

Title: Tweak receptor

Abstract: The present invention provides the TWEAK receptor and methods for identifying and using agonists and antagonists of the TWEAK receptor. In particular, the invention provides methods of screening for agonists and antagonists and for treating diseases or conditions mediated by angiogenesis, such as solid tumors and vascular deficiencies of cardiac or peripheral tissue.

Inventors: Wiley; Steven R. (Seattle, WA)

Assignee: Immunex Corporation

International Classification: A61K 39/395 (20060101); G01N 33/535 (20060101); C07K 16/28 (20060101); C07K 16/30 (20060101); G01N 33/532 (20060101); G01N 33/533 (20060101); G01N 33/534 (20060101)

Expiration Date: 5/13/12018